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Genetics

Visceral obesity stimulates anaphase bridge formation and spindle assembly checkpoint dysregulation in radioresistant oesophageal adenocarcinoma

A. M. Mongan; N. Lynam-Lennon; R. Casey; S. Maher; G. Pidgeon; J. V. Reynolds; J. O’Sullivan Visceral obesity stimulates anaphase bridge formation and spindle assembly checkpoint dysregulation in radioresistant oesophageal adenocarcinoma Clinical and Translational Oncology
Genetics

MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review

L. Dowling; A. Duseja; T. Vilaca; J. S. Walsh; K. Goljanek-Whysall MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review J Cachexia Sarcopenia Muscle
Genetics

The SGBS cell strain as a model for the in vitro study of obesity and cancer

E. H. Allott; E. Oliver; J. Lysaght; S. G. Gray; J. V. Reynolds; H. M. Roche; G. P. Pidgeon The SGBS cell strain as a model for the in vitro study of obesity and cancer Clin Transl Oncol
Genetics

MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation

E. H. Allott; J. Lysaght; M. C. Cathcart; C. L. Donohoe; R. Cummins; S. A. McGarrigle; E. Kay; J. V. Reynolds; G. P. Pidgeon MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation Mol Carcinog
Genetics

Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study

C. F. Hung; M. Rivera; N. Craddock; M. J. Owen; M. Gill; A. Korszun; W. Maier; O. Mors; M. Preisig; J. P. Rice; M. Rietschel; L. Jones; L. Middleton; K. J. Aitchison; O. S. Davis; G. Breen; C. Lewis; A. Farmer; P. McGuffin Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study Br J Psychiatry
Genetics

Age- and duration-dependent effects of whey protein on high-fat diet-induced changes in body weight, lipid metabolism, and gut microbiota in mice

S. Boscaini; R. Cabrera-Rubio; O. Nychyk; J. Roger Speakman; J. Francis Cryan; P. David Cotter; K. N. Nilaweera Age- and duration-dependent effects of whey protein on high-fat diet-induced changes in body weight, lipid metabolism, and gut microbiota in mice Physiol Rep
Genetics

Depletion of the gut microbiota differentially affects the impact of whey protein on high-fat diet-induced obesity and intestinal permeability

S. Boscaini; R. Cabrera-Rubio; A. Golubeva; O. Nychyk; C. Fülling; J. R. Speakman; P. D. Cotter; J. F. Cryan; K. N. Nilaweera Depletion of the gut microbiota differentially affects the impact of whey protein on high-fat diet-induced obesity and intestinal permeability Physiol Rep
Genetics

Multivariate analysis of genome-wide data to identify potential pleiotropic genes for type 2 diabetes, obesity and coronary artery disease using MetaCCA

X. Jia; Y. Yang; Y. Chen; Z. Xia; W. Zhang; Y. Feng; Y. Li; J. Tan; C. Xu; Q. Zhang; H. Deng; X. Shi Multivariate analysis of genome-wide data to identify potential pleiotropic genes for type 2 diabetes, obesity and coronary artery disease using MetaCCA International Journal of Cardiology
Genetics Insulin Resistance & Diabetes

miR-107: a toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes

N. H. Foley; L. A. O'Neill miR-107: a toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes J Leukoc Biol
Genetics Insulin Resistance & Diabetes

UCP1 governs liver extracellular succinate and inflammatory pathogenesis

E. L. Mills; C. Harmon; M. P. Jedrychowski; H. Xiao; R. Garrity; N. V. Tran; G. A. Bradshaw; A. Fu; J. Szpyt; A. Reddy; H. Prendeville; N. N. Danial; S. P. Gygi; L. Lynch; E. T. Chouchani UCP1 governs liver extracellular succinate and inflammatory pathogenesis Nat Metab
Genetics NAFLD

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