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Genetics

The Gut Microbiota Profile in Children with Prader-Willi Syndrome

Y. Peng; Q. Tan; S. Afhami; E. C. Deehan; S. Liang; M. Gantz; L. Triador; K. L. Madsen; J. Walter; H. M. Tun; A. M. Haqq The Gut Microbiota Profile in Children with Prader-Willi Syndrome Genes (Basel)
Dietary Studies Genetics

Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction

E. Giannoudaki; Y. E. Hernandez-Santana; K. Mulfaul; S. L. Doyle; E. Hams; P. G. Fallon; A. Mat; D. O'Shea; M. Kopf; A. E. Hogan; P. T. Walsh Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction Nat Commun
Animal Studies Genetics Insulin resistance & diabetes T2DM Weight loss / Management

Age- and duration-dependent effects of whey protein on high-fat diet-induced changes in body weight, lipid metabolism, and gut microbiota in mice

S. Boscaini; R. Cabrera-Rubio; O. Nychyk; J. Roger Speakman; J. Francis Cryan; P. David Cotter; K. N. Nilaweera Age- and duration-dependent effects of whey protein on high-fat diet-induced changes in body weight, lipid metabolism, and gut microbiota in mice Physiol Rep
Genetics

Depletion of the gut microbiota differentially affects the impact of whey protein on high-fat diet-induced obesity and intestinal permeability

S. Boscaini; R. Cabrera-Rubio; A. Golubeva; O. Nychyk; C. Fülling; J. R. Speakman; P. D. Cotter; J. F. Cryan; K. N. Nilaweera Depletion of the gut microbiota differentially affects the impact of whey protein on high-fat diet-induced obesity and intestinal permeability Physiol Rep
Genetics

Multivariate analysis of genome-wide data to identify potential pleiotropic genes for type 2 diabetes, obesity and coronary artery disease using MetaCCA

X. Jia; Y. Yang; Y. Chen; Z. Xia; W. Zhang; Y. Feng; Y. Li; J. Tan; C. Xu; Q. Zhang; H. Deng; X. Shi Multivariate analysis of genome-wide data to identify potential pleiotropic genes for type 2 diabetes, obesity and coronary artery disease using MetaCCA International Journal of Cardiology
Genetics T2DM

Endurance exercise training programs intestinal lipid metabolism in a rat model of obesity and type 2 diabetes

Y. H. Hung; M. A. Linden; A. Gordon; R. S. Rector; K. K. Buhman Endurance exercise training programs intestinal lipid metabolism in a rat model of obesity and type 2 diabetes Physiol Rep
Genetics T2DM Weight loss / Management

A randomised controlled trial of a duodenal-jejunal bypass sleeve device (EndoBarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes mellitus

M. A. Glaysher; A. Mohanaruban; C. G. Prechtl; A. P. Goldstone; A. D. Miras; J. Lord; N. Chhina; E. Falaschetti; N. A. Johnson; W. Al-Najim; C. Smith; J. V. Li; M. Patel; A. R. Ahmed; M. Moore; N. Poulter; S. Bloom; A. Darzi; C. Le Roux; J. P. Byrne; J. P A randomised controlled trial of a duodenal-jejunal bypass sleeve device (EndoBarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes mellitus BMJ Open
Appetite and Satiety Basic Science Genetics T2DM Weight loss / Management

miR-107: a toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes

N. H. Foley; L. A. O'Neill miR-107: a toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes J Leukoc Biol
Genetics T2DM

UCP1 governs liver extracellular succinate and inflammatory pathogenesis

E. L. Mills; C. Harmon; M. P. Jedrychowski; H. Xiao; R. Garrity; N. V. Tran; G. A. Bradshaw; A. Fu; J. Szpyt; A. Reddy; H. Prendeville; N. N. Danial; S. P. Gygi; L. Lynch; E. T. Chouchani UCP1 governs liver extracellular succinate and inflammatory pathogenesis Nat Metab
Genetics NAFLD

Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome

A. M. J. Van Hees; J. W. E. Jocken; Y. Essers; H. M. Roche; W. H. M. Saris; E. E. Blaak Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome Metabolism: Clinical and Experimental
Cholesterol Genetics Insulin resistance & diabetes Metabolic Syndrome

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