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Genetics

The advent of RNA-based therapeutics for metabolic syndrome and associated conditions: a comprehensive review of the literature

Huang HYR, Badar S, Said M, Shah S, Bharadwaj HR, Ramamoorthy K, Alrawashdeh MM, Haroon F, Basit J, Saeed S, Aji N, Tse G, Roy P, Bardhan M. The advent of RNA-based therapeutics for metabolic syndrome and associated conditions: a comprehensive review of the literature Mol Biol Rep
Genetics

Duodenal enteroendocrine cells and GIP as treatment targets for obesity and type 2 diabetes

Bailey CJ, Flatt PR. Duodenal enteroendocrine cells and GIP as treatment targets for obesity and type 2 diabetes Peptides
Genetics

Body weight, behaviours of concern, and social contact in adults and adolescents with Prader-Willi syndrome in full-time care services: Findings from pooled international archival data

Hughes BM, Holland A, Hödebeck-Stuntebeck N, Garrick L, Goldstone AP, Lister M, Moore C, Hughes M. Body weight, behaviours of concern, and social contact in adults and adolescents with Prader-Willi syndrome in full-time care services: Findings from pooled international archival data Orphanet J Rare Dis
Genetics

Oligogenic inheritance in severe adult obesity

Almansoori S, Alsters SI, Yiorkas AM, Nor Hashim NA, Walters RG, Chahal HS, Purkayastha S, Lessan N, Blakemore AIF. Oligogenic inheritance in severe adult obesity Int J Obes (Lond)
Genetics

Register-based and genetic studies of Prader-Willi syndrome show a high frequency of gonadal tumors and a possible mechanism for tumorigenesis through imprinting relaxation

Maya-González C, Wessman S, Lagerstedt-Robinson K, Taylan F, Tesi B, Kuchinskaya E, McCluggage WG, Poluha A, Holm S, Nergårdh R, Díaz De Ståhl T, Höybye C, Tettamanti G, Delgado-Vega AM, Skarin Nordenvall A, Nordgren A. Register-based and genetic studies of Prader-Willi syndrome show a high frequency of gonadal tumors and a possible mechanism for tumorigenesis through imprinting relaxation Front Med (Lausanne)
Genetics

Börjeson-Forssman-Lehmann syndrome: delineating the clinical and allelic spectrum in 14 new families

Jain V, Foo SH, Chooi S, Moss C, Goodwin R, Berland S, Clarke AJ, Davies SJ, Corrin S, Murch O, Doyle S, Graham GE, Greenhalgh L, Holder SE, Johnson D, Kumar A, Ladda RL, Sell S, Begtrup A, Lynch SA, McCann E, Østern R, Pottinger C, Splitt M, Fry AE. Börjeson-Forssman-Lehmann syndrome: delineating the clinical and allelic spectrum in 14 new families Eur J Hum Genet
Genetics

Polymorphisms of Fat Mass and Obesity-Associated Gene in the Pathogenesis of Child and Adolescent Metabolic Syndrome

Song Y, Wade H, Zhang B, Xu W, Wu R, Li S, Su Q. Polymorphisms of Fat Mass and Obesity-Associated Gene in the Pathogenesis of Child and Adolescent Metabolic Syndrome Nutrients
Genetics

Sex differences in the association between dynapenic abdominal obesity and onset of disability in activities of daily living among adults aged ≥50 years: A prospective analysis of the Irish Longitudinal Study on Ageing

Smith L, López Sánchez GF, Tully MA, Veronese N, Soysal P, Yon DK, Pizzol D, López-Gil JF, Barnet Y, Butler L, Shin JI, Koyanagi A. Sex differences in the association between dynapenic abdominal obesity and onset of disability in activities of daily living among adults aged ≥50 years: A prospective analysis of the Irish Longitudinal Study on Ageing Maturitas
Genetics

Truncating homozygous mutation of carboxypeptidase E (CPE) in a morbidly obese female with type 2 diabetes mellitus, intellectual disability and hypogonadotrophic hypogonadism

S. I. M. Alsters; A. P. Goldstone; J. L. Buxton; A. Zekavati; A. Sosinsky; A. M. Yiorkas; S. Holder; R. E. Klaber; N. Bridges; M. M. Van Haelst; C. W. L. Roux; A. J. Walley; R. G. Walters; M. Mueller; A. I. F. Blakemore Truncating homozygous mutation of carboxypeptidase E (CPE) in a morbidly obese female with type 2 diabetes mellitus, intellectual disability and hypogonadotrophic hypogonadism PLoS ONE
Genetics Insulin Resistance & Diabetes

The impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study

C. B. O'Donovan; M. C. Walsh; H. Forster; C. Woolhead; C. Celis-Morales; R. Fallaize; A. L. Macready; C. F. Marsaux; S. Navas-Carretero; R. San-Cristobal; S. Kolossa; C. Mavrogianni; C. P. Lambrinou; G. Moschonis; M. Godlewska; A. Surwillo; J. Bouwman; K. The impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study Genes Nutr
Genetics

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