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Publication Category: Metabolic Health

Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice

V. Parthsarathy; C. Hogg; P. R. Flatt; F. P. M. O'Harte Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice Diabetes Obes Metab
Cholesterol Insulin Resistance & Diabetes

Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice

F. P. M. O'Harte; V. Parthsarathy; C. Hogg; P. R. Flatt Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice PLoS One
Insulin Resistance & Diabetes

Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice

O. O. Ojo; D. K. Srinivasan; B. O. Owolabi; J. M. Conlon; P. R. Flatt; Y. H. A. Abdel-Wahab Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice Biochim Biophys Acta
Insulin Resistance & Diabetes

Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study

V. Musale; R. C. Moffett; J. M. Conlon; P. R. Flatt; Y. H. Abdel-Wahab Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study
Genetics Insulin Resistance & Diabetes

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice

L. M. McShane; N. Irwin; D. O'Flynn; Z. J. Franklin; C. M. Hewage; F. P. O'Harte Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice J Endocrinol
Insulin Resistance & Diabetes

Medications Activating Tubular Fatty Acid Oxidation Enhance the Protective Effects of Roux-en-Y Gastric Bypass Surgery in a Rat Model of Early Diabetic Kidney Disease

W. P. Martin; Y. H. D. Chuah; M. Abdelaal; A. Pedersen; D. Malmodin; S. Abrahamsson; M. Hutter; C. Godson; E. P. Brennan; L. Fändriks; C. W. le Roux; N. G. Docherty Medications Activating Tubular Fatty Acid Oxidation Enhance the Protective Effects of Roux-en-Y Gastric Bypass Surgery in a Rat Model of Early Diabetic Kidney Disease Front Endocrinol (Lausanne)
Chronic Kidney Disease Insulin Resistance & Diabetes

Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice

F. C. McGillicuddy; C. M. Reynolds; O. Finucane; E. Coleman; K. A. Harford; C. Grant; D. Sergi; L. M. Williams; K. H. Mills; H. M. Roche Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice Am J Physiol Endocrinol Metab
Insulin Resistance & Diabetes

Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1β secretion from adipose tissue: The implications for obesity-impaired reverse cholesterol transport

S. Kajani; S. Curley; M. E. O'Reilly; X. Yin; E. T. Dillon; W. Guo; K. N. Nilaweera; L. Brennan; H. M. Roche; F. C. McGillicuddy Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1β secretion from adipose tissue: The implications for obesity-impaired reverse cholesterol transport Mol Metab
Cholesterol

Obesity depresses baroreflex control of renal sympathetic nerve activity and heart rate in Sprague Dawley rats: Role of the renal innervation

S. A. Khan; M. Z. A. Sattar; N. A. Abdullah; H. A. Rathore; M. H. Abdulla; A. Ahmad; E. J. Johns Obesity depresses baroreflex control of renal sympathetic nerve activity and heart rate in Sprague Dawley rats: Role of the renal innervation Acta Physiol (Oxf)

Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes

N. Irwin; P. Frizelle; I. A. Montgomery; R. C. Moffett; F. P. M. O'Harte; P. R. Flatt Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes Diabetologia
Insulin Resistance & Diabetes

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