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Publication Category: Animal Studies

Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice

W. D. Porter; P. R. Flatt; C. Hölscher; V. A. Gault Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice Int J Obes (Lond)

Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice

N. M. Pathak; P. J. B. Millar; V. Pathak; P. R. Flatt; V. A. Gault Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice Mol Cell Endocrinol
Cholesterol Insulin Resistance & Diabetes

Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N- and C-terminal modifications improves obesity and metabolic control in high fat fed mice

V. Pathak; V. A. Gault; P. R. Flatt; N. Irwin Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N- and C-terminal modifications improves obesity and metabolic control in high fat fed mice Mol Cell Endocrinol
Appetite & Satiety Insulin Resistance & Diabetes

Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice

V. Parthsarathy; C. Hogg; P. R. Flatt; F. P. M. O'Harte Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice Diabetes Obes Metab
Cholesterol Insulin Resistance & Diabetes

Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice

F. P. M. O'Harte; V. Parthsarathy; C. Hogg; P. R. Flatt Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice PLoS One
Insulin Resistance & Diabetes

Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice

O. O. Ojo; D. K. Srinivasan; B. O. Owolabi; J. M. Conlon; P. R. Flatt; Y. H. A. Abdel-Wahab Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice Biochim Biophys Acta
Insulin Resistance & Diabetes

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity

D. Menon; A. Innes; A. J. Oakley; J. E. Dahlstrom; L. M. Jensen; A. Brüstle; P. Tummala; M. Rooke; M. G. Casarotto; J. B. Baell; N. Nguyen; Y. Xie; M. Cuellar; J. Strasser; J. L. Dahlin; M. A. Walters; G. Burgio; L. A. J. O'Neill; P. G. Board GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity Sci Rep

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice

M. J. Morine; S. Toomey; F. C. McGillicuddy; C. M. Reynolds; K. A. Power; J. A. Browne; C. Loscher; K. H. Mills; H. M. Roche Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice J Nutr Biochem
Insulin Resistance & Diabetes

Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study

V. Musale; R. C. Moffett; J. M. Conlon; P. R. Flatt; Y. H. Abdel-Wahab Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study
Genetics Insulin Resistance & Diabetes

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice

L. M. McShane; N. Irwin; D. O'Flynn; Z. J. Franklin; C. M. Hewage; F. P. O'Harte Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice J Endocrinol
Insulin Resistance & Diabetes

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