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Publication Category: Animal Studies

GLP-1 receptor agonism and GIP receptor antagonism induce substantial alterations in enteroendocrine and islet cell populations in obese high fat fed mice

Sridhar A, Khan D, Flatt PR, Moffett CR, Irwin N. GLP-1 receptor agonism and GIP receptor antagonism induce substantial alterations in enteroendocrine and islet cell populations in obese high fat fed mice Peptides

Chronic Semaglutide Treatment in Rats Leads to Daily Excessive Concentration-Dependent Sucrose Intake

Cawthon CR, Blonde GD, Nisi AV, Bloomston HM, Krubitski B, le Roux CW, Spector AC. Chronic Semaglutide Treatment in Rats Leads to Daily Excessive Concentration-Dependent Sucrose Intake J Endocr Soc

Serum Ferritin in Obese Dogs: Changes and Comparison with Other Analytes

Franco-Martínez L, Pardo-Marín L, Sánchez-Mateos L, Muñoz-Prieto A, García-Martínez JD, Cerón JJ, Martínez-Subiela S, Rubio CP, Tvarijonaviciute A. Serum Ferritin in Obese Dogs: Changes and Comparison with Other Analytes Vet Sci

GIP analogues augment bone strength by modulating bone composition in diet-induced obesity in mice

S. S. Vyavahare; A. Mieczkowska; P. R. Flatt; D. Chappard; N. Irwin; G. Mabilleau GIP analogues augment bone strength by modulating bone composition in diet-induced obesity in mice Peptides

Beneficial effects of tigerinin-1R on glucose homeostasis and beta cell function in mice with diet-induced obesity-diabetes

O. O. Ojo; D. K. Srinivasan; B. O. Owolabi; P. R. Flatt; Y. H. A. Abdel-Wahab Beneficial effects of tigerinin-1R on glucose homeostasis and beta cell function in mice with diet-induced obesity-diabetes Biochimie
Appetite & Satiety Insulin Resistance & Diabetes

A novel DPP IV-resistant C-terminally extended glucagon analogue exhibits weight-lowering and diabetes-protective effects in high-fat-fed mice mediated through glucagon and GLP-1 receptor activation

A. M. Lynch; N. Pathak; V. Pathak; F. P. M. O’Harte; P. R. Flatt; N. Irwin; V. A. Gault A novel DPP IV-resistant C-terminally extended glucagon analogue exhibits weight-lowering and diabetes-protective effects in high-fat-fed mice mediated through glucagon and GLP-1 receptor activation Diabetologia

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

H. Y. Kim; H. J. Lee; Y. J. Chang; M. Pichavant; S. A. Shore; K. A. Fitzgerald; Y. Iwakura; E. Israel; K. Bolger; J. Faul; R. H. DeKruyff; D. T. Umetsu Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity Nat Med

Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice

N. Irwin; I. A. Montgomery; R. C. Moffett; P. R. Flatt Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice Biochem Pharmacol
Insulin Resistance & Diabetes

Comparison of the independent and combined metabolic effects of subchronic modulation of CCK and GIP receptor action in obesity-related diabetes

N. Irwin; I. A. Montgomery; F. P. O'Harte; P. Frizelle; P. R. Flatt Comparison of the independent and combined metabolic effects of subchronic modulation of CCK and GIP receptor action in obesity-related diabetes Int J Obes (Lond)
Insulin Resistance & Diabetes

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

L. Lynch; M. Nowak; B. Varghese; J. Clark; A. Hogan; V. Toxavidis; S. Balk; D. O'Shea; C. O'Farrelly; M. Exley Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production Immunity

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