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Publication Category: Metabolic Health

Early weight loss responders to liraglutide 3.0mg had greater weight loss, regression to normoglycaemia, and reduced Type 2 diabetes development at three years vs early non-responders: SCALE Obesity and Prediabetes

C. W. Le Roux; D. C. W. Lau; K. Fujioka; F. Greenway; J. P. H. Wilding; P. B. Jacobsen; T. Skjoth; S. Madsbad Early weight loss responders to liraglutide 3.0mg had greater weight loss, regression to normoglycaemia, and reduced Type 2 diabetes development at three years vs early non-responders: SCALE Obesity and Prediabetes Diabetic medicine
Insulin Resistance & Diabetes

Liraglutide; A new hope for obese diabetics

A. Kumar; D. Kumar; S. Razzaque; A. Kumar; R. Kumar; M. I. Ghauri; M. Yaseen Liraglutide; A new hope for obese diabetics Journal of the Liaquat University of Medical and Health Sciences
Insulin Resistance & Diabetes

3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial

C. W. le Roux; A. Astrup; K. Fujioka; F. Greenway; D. C. W. Lau; L. Van Gaal; R. V. Ortiz; J. P. H. Wilding; T. V. Skjøth; L. S. Manning; X. Pi-Sunyer 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial Lancet
Insulin Resistance & Diabetes

Will medications that mimic gut hormones or target their receptors eventually replace bariatric surgery?

A. Kokkinos; D. Tsilingiris; C. W. le Roux; F. Rubino; C. S. Mantzoros Will medications that mimic gut hormones or target their receptors eventually replace bariatric surgery? Metabolism
Insulin Resistance & Diabetes

Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial

D. S. Feig; L. E. Donovan; B. Zinman; J. J. Sanchez; E. Asztalos; E. A. Ryan; I. G. Fantus; E. Hutton; A. B. Armson; L. L. Lipscombe; D. Simmons; J. F. R. Barrett; P. J. Karanicolas; S. Tobin; H. D. McIntyre; S. Y. Tian; G. Tomlinson; K. E. Murphy; D. Fei Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial The Lancet Diabetes and Endocrinology
Insulin Resistance & Diabetes

Enteroendocrine hormone mimetics for the treatment of obesity and diabetes

N. Irwin; P. R. Flatt Enteroendocrine hormone mimetics for the treatment of obesity and diabetes Curr Opin Pharmacol
Insulin Resistance & Diabetes

Clinical Impact of Liraglutide as a Treatment of Obesity

H. Alruwaili; B. Dehestani; C. W. le Roux Clinical Impact of Liraglutide as a Treatment of Obesity Clin Pharmacol

Recent advances in peptide-based therapy for Type 2 diabetes and obesity

J. M. Conlon; P. R. Flatt; C. J. Bailey Recent advances in peptide-based therapy for Type 2 diabetes and obesity Peptides
Insulin Resistance & Diabetes

Efficacy of metformin and fermentable fiber combination therapy in adolescents with severe obesity and insulin resistance: study protocol for a double-blind randomized controlled trial

E. C. Deehan; E. Colin-Ramirez; L. Triador; K. L. Madsen; C. M. Prado; C. J. Field; G. D. C. Ball; Q. Tan; C. Orsso; I. Dinu; M. Pakseresht; D. Rubin; A. M. Sharma; H. Tun; J. Walter; C. B. Newgard; M. Freemark; E. Wine; A. M. Haqq Efficacy of metformin and fermentable fiber combination therapy in adolescents with severe obesity and insulin resistance: study protocol for a double-blind randomized controlled trial Trials
Insulin Resistance & Diabetes

Integrated insights into the role of alpha-melanocyte stimulatory hormone in the control of food intake and glycaemia

W. Al-Najim; C. W. le Roux; N. G. Docherty Integrated insights into the role of alpha-melanocyte stimulatory hormone in the control of food intake and glycaemia Peptides
Appetite & Satiety

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