A genome-wide association meta-analysis identifies new childhood obesity loci
- Categories: Basic Science, Childhood
- Tags Genetics
Type Article
Journal Article
Authors
J. P. Bradfield; H. R. Taal; N. J. Timpson; A. Scherag; C. Lecoeur; N. M. Warrington; E. Hypponen; C. Holst; B. Valcarcel; E. Thiering; R. M. Salem; F. R. Schumacher; D. L. Cousminer; P. M. A. Sleiman; J. Zhao; R. I. Berkowitz; K. S. Vimaleswaran; I. Jari
Year of publication
2012
Publication/Journal
Nature Genetics
Volume
44
Issue
5
Pages
526-531
Abstract
Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Australian and European collaborative meta-analysis of 14 studies consisting of 5,530 cases (≥95th percentile of body mass index (BMI)) and 8,318 controls (