Remission of type 2 diabetes in patients undergoing biliointestinal bypass for morbid obesity: a new surgical treatment

Categories: Bariatric Surgery, Metabolic Health, Severe Obesity

Tags Insulin Resistance & Diabetes

Type Article

Journal Article

Authors

G. Del Genio; M. Gagner; P. Limongelli; S. Tolone; D. Pournaras; C. W. le Roux; L. Brusciano; A. Licia Mozzillo; F. Del Genio; L. Docimo

Year of publication

2016

Publication/Journal

Surg Obes Relat Dis

Volume

Issue

Pages

815-821

Abstract

BACKGROUND: Nutrient interaction with the mid-gut may play a role in improving type 2 diabetes mellitus (T2D) after bariatric surgery. However, Roux-en-Y gastric bypass, biliopancreatic diversion, and sleeve gastrectomy include diversion of food from the duodenum and/or partial gastrectomy. Biliointestinal bypass (BIBP) was introduced to eliminate the major side effects of jejunoileal bypass. It does not involve any change to the anatomy of the stomach or the duodenum. A prospective evaluation of the role of BIBP in glycemic control has not been reported. OBJECTIVES: Longitudinal evaluation of T2D after BIBP. SETTING: University hospitals in Europe and Canada. METHOD: The effects of BIBP on metabolism and glycemia in 28 consecutive patients with T2D were evaluated over 2 years. RESULTS: Decreases (P