Evaluation of Heart Rate Variability and Endothelial Function 3 Months After Bariatric Surgery

Type Article

Journal Article

Authors

T. Gomide Braga; M. das Graças Coelho de Souza; P. A. Maranhão; M. Menezes; L. Dellatorre-Teixeira; E. Bouskela; C. W. Le Roux; L. G. Kraemer-Aguiar

Year of publication

2020

Publication/Journal

Obes Surg

Volume

30

Issue

6

Pages

2450-2453

Abstract

We investigated endothelial and autonomic nervous functions after bariatric surgery. For this, we prospectively recruited 40 patients for bariatric surgery or medical treatment (20 in each group). Heart rate variability (HRV) and endothelial function were evaluated before and 3 months after treatments. Glucagon-like peptide 1 (GLP-1), insulin, and glucose at fasting and 30 and 60 min after a standard 300-kcal meal were also analyzed. Surgery but not medical care increased HRV in all time-domain variables, while frequency-domain variables, vascular elasticity, and endothelial reactivity did not change. Changes in GLP-1 and insulin resistance markers did not correlate with HRV. After 3 months, bariatric surgery improved the parasympathetic activity of cardiac autonomic function. Trial registration: NCT03911479.