Comparison of Efficacy and Safety of Liraglutide 3.0 mg in Individuals with BMI above and below 35 kg/m2: A Post-hoc Analysis

Type Article

Journal Article

Authors

C. Le Roux; V. Aroda; J. Hemmingsson; A. P. Cancino; R. Christensen; X. Pi-Sunyer

Year of publication

2018

Publication/Journal

Obesity Facts

Volume

10

Issue

6

Pages

531-544

Abstract

Objective: To investigate whether the efficacy and safety of liraglutide 3.0 mg differed between two subgroups, BMI 27 to 0.05). Similarly, for most secondary endpoints significantly greater improvements were observed with liraglutide 3.0 mg versus placebo, with no indication treatment effects differing between subgroups. The safety profile of liraglutide 3.0 mg was broadly similar across BMI subgroups. Conclusion: This post-hoc analysis did not indicate any differences in the treatment effects, or safety profile, of liraglutide 3.0 mg for individuals with BMI 27 to