Comparison of Efficacy and Safety of Liraglutide 3.0 mg in Individuals with BMI above and below 35 kg/m2: A Post-hoc Analysis
- Categories: Medications, Metabolic Health, Weight Loss/Management
Type Article
Journal Article
Authors
C. Le Roux; V. Aroda; J. Hemmingsson; A. P. Cancino; R. Christensen; X. Pi-Sunyer
Year of publication
2018
Publication/Journal
Obesity Facts
Volume
10
Issue
6
Pages
531-544
Abstract
Objective: To investigate whether the efficacy and safety of liraglutide 3.0 mg differed between two subgroups, BMI 27 to 0.05). Similarly, for most secondary endpoints significantly greater improvements were observed with liraglutide 3.0 mg versus placebo, with no indication treatment effects differing between subgroups. The safety profile of liraglutide 3.0 mg was broadly similar across BMI subgroups. Conclusion: This post-hoc analysis did not indicate any differences in the treatment effects, or safety profile, of liraglutide 3.0 mg for individuals with BMI 27 to